mesofiller logo

Highly purifed, crosslinked, monophasic hyaluronic acid mesofiller

a new range of high quality, highly purified, monophasic hyaluronic acid dermal fillers

Obtained from a biofermentation process
transparent viscoelastic gel
biocompatible and totally resorbable; integrates naturally into skin
indicated for correction of wrinkles and restoration of facial volume
DENSIMATRIX TECHNOLOGY® Innovation by mesoestic®


tickmesoestetic always guarantees the excellence of the manufacturing process of its products. mesofiller has been produced with the E.P.P.S. (Esterilization Permanent Production System).

tickmesofiller holds the CE 0373 marking in compliance with the European directive on medical devices, MDD 93/42/CEE.

tickManufactured under GMP standards and in conformance with ISO 13485 and ISO 9001 standards.

tickBiocompatibility studies performed in conformance with ISO 10993 guidelines.

tickState-of-the-art sterilization process guaranteed by mesoestetic Pharma Group.

Indications – click to enlarge


mesofiller global

mesofiller global

mesofiller intense

mesofiller intense

Efficacy and safety studies in various areas of application.

Efficacy – Safety and efficacy study

Treatment group
Thirty volunteers over 18 years of age with any skin type, exhibiting signs of aging, that can be corrected by the infiltration of a hyaluronic acid filler were enrolled in the study.
An assessment of the degree of aging using WSRS (Wrinkle Severity Rating Scale) in order to apply the most suitable mesofiller for each volunteer
Application of an anaesthetic or cold cream
Injection of the filler on the area to be treated in a single session
Touch-up 15 days later, in those cases deemed necessary
Assessment of efficacy using the Global Aesthetic Improvement Scale (GAIS)
Likert type satisfaction survey

before and after 1 before and after 2 before and after 3 before and after 4 before and after 5 before and after 6 efficacy study results