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cosmelan® is the worldwide benchmark depigmentation method that acts on skin spots on a visible and integral manner. A professional method that provides an intensive corrective action combined with a potent action that regulates the formation of new melanin, essential to provide a short and long-term result.

Over one million patients all over the world and thousands of professionals support cosmelan® as a preferred depigmentation method to treat the most severe, resistant hyperpigmentations with maximum efficacy and safety for the dermis.


Pigmentation concerns are a growing, global issue; they affect more than 90% of adults over the age of 50. Regardless of skin color, they are a significant issue because of their unattractive appearance and negative psychological and emotional impact, affecting quality of life.

Skin hyperpigmentation is caused by abnormal production of melanin, the pigment responsible for skin color, and is a consequence of uncontrolled, localized overproduction of melanin by the melanocytes, causing irregular skin coloration and dark spots.

Types of spots


Due to hormonal changes or contraceptive treatments.

Located on: cheeks, upper lip, forehead and chin.

Post-inflammatory hyperpigmentation (PIH)

After inflammatory conditions: acne, depilation, aggressive treatments, etc. Higher risk in dark skins.

Located on: face and body

Solar and senile lentigo

Due to occasional or cumulative sun overexposure, in particular with age (photoaging) in the areas with a greater sun exposure.

Located on: face, back of the hands, décolletage.

Ephelides (freckles)

Characteristic of clear skin and with a strong genetic component.

Located on: face and body.

cosmelan®: what is it and what does it consist of?

cosmelan® is a depigmenting method that removes spots fully and prevents their reappearance for a short-term outcome, while being able to maintain hyperpigmentations under control for a longlasting outcome.

The cosmelan® method consists of 4-phases which are necessary to achieve the target outcome. Intense depigmentation in cabin in phase 1 and treatment for home use in phases 2, 3 and 4.

Efficacy studies support its success in all types of skin, hyperpigmentations and ethnicities.

Stages and treatment results

1. intensive depigmentation


Clock 8 - 12 h

Apply the oil removing solution using a gauze over the clean, dry skin. Then apply cosmelan 1 mask homogeneously all over the face, not only on hyperpigmented areas.

Apply the product using a spatula or with a gloved hand. Avoid eye contour.

To achieve the maximum efficacy, it is recommended to apply the entire product, 10 g. It is important to ensure that the mask remains wet throughout its use.

A water spray may be used to prevent that it gets dry.

Apply the treatment on the skin for the recommended time according to the phototype, the degree of severity of the blemish and the type of skin, always subject to the criterion of the professional.

Removal of cosmelan 1

After the time indicated by the professional, the patient should carefully rinse cosmelan 1 mask out with plenty of tepid water.

Repeat as often as required to remove the product completely.

2. Continuous depigmentation


Clock 1 month

48-72 hours after removing the mask, treatment continues.

Apply cosmelan 2 three times a day (morning, midday and night) followed by melan recovery and melan 130+ pigment control during daytime applications.

3. Control of hyperpigmentation


Clock 2 months

Apply cosmelan 2 day and night, followed by melan recovery and melan 130+ pigment control at daytime. In case of sun exposure, reapply sunscreen at midday.

4. Control de reaparición


Clock 3 months

Apply cosmelan 2 at night, followed by melan recovery. At daytime, apply melan 130+ pigment control and reapply in case of direct sun exposure.

Treatment results

Before Before
Melasma (phototype I-III)
Before Before
Senile lentigo (phototype I-III)